Sildenafil Research – What is Sildenafil Citrate?

Sildenafil research studies from the recent years are available and all of them led to the development of Sildenafil Citrate as a drug for erectile dysfunction. Sildenafil Citrate is developed by the company Pfizer and popularized as the drug Viagra. Viagra, since 1998, has become the gold standard for impotence treatment in males. Sildenafil Citrate is the first PDE5 inhibitor drug available in the market and is the drug which started the wave of impotence-busting treatments, like the drugs Cialis, Staxyn, and Levitra.

What is Sildenafil Citrate?

Sildenafil Citrate is classified as a PDE5 inhibitor drug and its primary goal is to suppress the action of the phosphodiesterase enzyme found in key tissues of the human body. For impotence treatment, Sildenafil allows smooth muscle relaxation and vasodilation in the penis tissues, hence allowing the patients to have stiffer, more sufficient erections whenever they are sexually aroused.

The drug Sildenafil Citrate is known by its trade name Viagra from Pfizer. It is available in doses of 25 mg, 50 mg, and 100 mg, and is recommended in patients with 25-100 mg, as needed, once in a 24-hour period. Since Sildenafil Citrate’s average duration in the body is only 4 hours, patients are advised to perform their sexual activities within 4 hours of the drug’s intake.

Sildenafil Citrate Tablets

Here are other key facts about the drug Sildenafil Citrate:

  • Uses: erectile dysfunction and pulmonary hypertension
  • Manufacturer (brand name): Viagra from Pfizer for erectile dysfunction; Revatio from Pfizer for pulmonary hypertension
  • Year of marketing and FDA Approval: 1998
  • Available strengths: For impotence: 25 mg, 50 mg, and 100 mg (in some cases, 150 mg and 200 mg); For pulmonary hypertension: 20 mg and 10 mg/mL
  • Dosage recommendations: 25 to 100 mg for erectile dysfunction; 2.5 to 20 mg for pulmonary hypertension
  • Drug interactions: nitrate drugs (nitroglycerin, isosorbide mono/dinitrate, poppers, and other nitrate-containing medicines), ketoconazole and related medicines, erythromycin and related medicines, ricoguat (Adempas), any blood pressure mitigating medicine, protease inhibitors, alpha blockers, and several others
  • Disease interactions: liver diseases, renal insufficiency, cancers, HIV/AIDS, and several others
  • Common side effects: headaches, low blood pressure, vision changes (blurred vision or blue vision), dizziness, and dyspepsia
  • Availability: Local drugstores (Viagra, Revatio, and Sildenafil 20 mg); online (generic alternatives)

What is Research Chemical Tadalafil?

Tadalafil, on the other hand, is one of the “latest” phosphodiesterase inhibitors developed for impotence treatment. Tadalafil is known as Cialis in the market and is developed by the massive and historical company, Eli Lilly, from the United States.

Tadalafil also belongs to the same drug family as the drug Sildenafil Citrate. However, this drug is slowly gaining more attention from consumers due to its significant effect in the patients—instead of the 4-hour effect of Sildenafil Citrate, Tadalafil presents a 36-hour effectiveness in the males.

Tadalafil – Cialis from Eli Lilly and Company

Tadalafil – Cialis from Eli Lilly and Company

Like Sildenafil Citrate, Cialis also has monopoly over the US market since it was able to hold off patent approvals for the generic versions of Cialis in the market. Pfizer and Eli Lilly’s monopoly over the US market put the consumers in a tough position—buyers protest against these drugs’ exorbitant prices and are left with no choice but to prefer the purchase of generic medicines online.

Here are some key facts about Tadalafil:

  • Uses: erectile dysfunction (ED), benign prostatic hyperplasia (BPH)
  • Manufacturer (brand name): Cialis from Eli Lilly
  • Year of marketing and FDA Approval: 2003
  • Available strengths: 2.5 and 5 mg for the daily use (for impotence and BPH); 10 mg and 20 mg for the as needed dose
  • Dosage recommendations: 2.5 mg to 5 mg daily for impotence or BPH; 10 mg to 20 mg on-demand for impotence
  • Drug interactions: nitrate drugs (nitroglycerin, isosorbide mono/dinitrate, poppers, and other nitrate-containing medicines), ketoconazole and related medicines, erythromycin and related medicines, ricoguat (Adempas), any blood pressure mitigating medicine, protease inhibitors, alpha blockers, and several others
  • Disease interactions: liver diseases, renal insufficiency, cancers, HIV/AIDS, and several others
  • Common side effects: back pain, myalgia, headaches, low blood pressure, dizziness, and dyspepsia
  • Availability: Local drugstores (Cialis 2.5, 5, 10, and 20 mg); online (generic alternatives)

Is There a Sildenafil Liquid Drug?

Besides the tablet and jelly forms of Sildenafil in the market, there also exists a liquid concentrate form of the product. There are local and online pharmacies selling this liquid Sildenafil product; however, the sale of this drug is somewhat restricted to chemists and researchers.

Sildenafil Citrate Liquid

Sildenafil Citrate Liquid

Buyers cannot simply avail of the Sildenafil Citrate liquid—they need to present a lab license or research license before they can have the drug. Unlike its tablet, jelly, and other oral counterparts, this Sildenafil Citrate liquid is not meant for human use; this drug is exclusively created for experimental purposes. Online pharmacies selling this drug also emphasize the “for research only” use of this drug, hence the restriction of the personal purchases for this product.

Buyers should not consider this a loss since there are multitudes of other Sildenafil Citrate forms available in the market. Consumers can choose from a wide variety of Sildenafil Citrate options on the web, especially from reliable online drugstores with nothing but genuine products in-stock. If you need references regarding where to buy your Sildenafil or Tadalafil drugs, you can use our list of Top Online Pharmacies for the present year.

Conclusion

Sildenafil research studies proved the effectiveness of Sildenafil Citrate as an agent for impotence treatment. These papers also paved the way for the development of the drug as a treatment for preliminary PAH. Sildenafil, through the years, has become reliable when it comes to erectile dysfunction and has also pioneered a new form of impotence treatment (systemic rather than invasive) in males, giving way to other forms of PDE5 inhibitor treatments like Cialis, Levitra, and Staxyn.

Brand name erectile dysfunction treatments like Viagra and Cialis are reliable (almost 100%), but since their prices are too steep, buyers may need to consider purchasing generic options online.